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**Figure 2-1:** The Photoshop interface and main tool bar. The rest of this chapter walks you through getting started with Photoshop. Introducing Photoshop Photoshop was created by Adobe Systems in 1990. The first Photoshop demonstration was given in 1991 at the company’s annual conference, where an image editor was shown working in a completely new way. This innovative software evolved into the industry standard for manipulating photographs and more. Photoshop is part of Adobe’s Creative Suite (formerly Photoshop Creative Suite) of software. Version History of Photoshop For some time, Photoshop has been the industry-leading software for photography. But not only does Photoshop address editing and retouching, it also includes features useful to other creatives, such as a vector program and the Adobe Creative Suite apps, and an image-format editor, all of which were added over time. Table 2-1 lists some of the editions. Table 2-1 Version History of Photoshop — Version | Release Date | Features Creative Suite 1.0 (CS1) | 1990 | Vector graphics editor, filter effects Creative Suite 1.0 (CS1) | 1994 | Layer based editing system, similar to layers in Word Creative Suite 2 (CS2) | 1995 | Content-aware tools, scaling, rotation, and skewing Creative Suite 2 (CS2) | 1998 | New edit commands, new file format.PSD, support for GIF and BMP formats, plug-ins for viewing other formats Creative Suite 2.5 (CS2.5) | 1998 | Improved resampling, multilayer capabilities Creative Suite 3 (CS3) | 2002 | Easily view image editing results as.PSD files, support for.EPS,.XCF,.TIFF,.GIF, and.JPG formats Creative Suite 4 (CS4) | 2003 | Refine tools for fonts, photo and vector shapes, introduce tools for backgrounds, and support for.PNG format Creative Suite 5 (CS5) | 2005 | Many new features in the Refine category, new version of Adobe Camera Raw (ACR), image management, find and replace tool, tool bar enhancements, layer based selection, and new filters Creative Suite 5.5 (CS5.5) | 2007 | Improved color, image management, improved layout controls, new toolbar options
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The difference between the standalone version of Photoshop Elements and Photoshop is in the program’s target market. Photoshop Elements is only designed to be an image editor for amateur photographers. It lacks features that professional users need, but it is a good alternative for users who aren’t familiar with the features of professional image editors. It is great for basic photo editing such as cropping, adding text, drawing shapes, and basic color correction. The standalone version of Photoshop is also a graphic editor, but it is designed to be professional and is much more powerful than Photoshop Elements. Some of its power comes from its ability to simultaneously work on multiple projects and several other applications at once. This edition of Photoshop can offer more complexity, but not all users can afford to have a separate system for managing all the programs on their computer. In the following article, we’ll take a look at how to use the image editor in Photoshop and Photoshop Elements to edit photos or designs. Requirements Before starting to edit images in Photoshop or Photoshop Elements, you will need a computer with a basic understanding of image editing. Your computer should have at least 2 GB of RAM (Random Access Memory), 2.5 GB of hard drive space (for installing Photoshop and any necessary software) and a good operating system, such as Windows 7 or newer. Installing Photoshop Elements and Photoshop On Windows, you can install both Photoshop and Photoshop Elements by using their installation discs. First, insert the installation disc into your computer’s drive. After it is installed, you can select the Photoshop program from the Start menu and launch it. You can also find the Photoshop program in the Programs folder within your computer’s operating system. Click the Start button and the type “Programs” in the search bar. On the result page, click “Software and Apps” and look for the Photoshop program in the results. The same method can be used to find the Photoshop Elements program. You can also download the program from Adobe’s website using the link on the Downloads page at the bottom of the program’s home page. It is recommended that you download the latest version of the program to keep up with the latest changes and improvements. Editing Images in Photoshop Photoshop is an advanced image editor that can be used to edit the structure, content, and appearance of images for many different reasons. It can help you create new images or edit existing ones and is commonly used for photo editing, 05a79cecff
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Cytochrome oxidase histochemistry in the human retina. Cytochrome oxidase activity was demonstrated in the retina by the technique of Karnovsky and Roots. The enzyme activity was confined to the inner nuclear layer and the inner plexiform layer. The enzyme activity was not distributed uniformly throughout the retina nor was the activity restricted to the dorsal or ventral retina. There was little difference in the distribution of enzyme activity between normal and senile subjects, but there was a tendency for the enzyme activity to be greater in the normal retina than in the senile retina. The distribution of enzyme activity in the human retina is therefore similar to that reported for other species. the pathogenesis of myocardial injury \[[@CR58]\]. Blood insulin concentrations increase in HF and in ischaemic heart disease, which can promote the expression of the NADPH oxidase subunits \[[@CR59]\]. The Nox5-targeted overexpression was associated with an increase in arterial pressure \[[@CR59]\]. This effect may be due to the endothelial increase in the generation of vasodilators as superoxide \[[@CR60]\]. These vasodilators include endothelial-derived hyperpolarizing factor, which attenuates the effects of the endothelium. Endothelial cell NADPH oxidase increases the production of superoxide that stimulates the synthesis of nitric oxide by mechanisms that remain to be clarified. In addition, the antioxidant vitamin C reduces the synthesis of endothelial-derived hyperpolarizing factor \[[@CR61], [@CR62]\]. Antioxidant therapy in HF {#Sec12} ========================= Several clinical trials have shown the effects of administering antioxidants in patients with HF. Nitric oxide is synthesized by the endothelium. In HF, a reduction in the synthesis of endothelial nitric oxide induces the production of reactive oxygen species and the modification of the endothelial function \[[@CR63]–[@CR65]\]. The administration of antioxidant vitamin E improves the endothelial function in HF patients \[[@CR66]\]. Supplementation of vitamin C and E in patients with HF reduced the plasma levels of MDA and improved the systolic function of the left ventricle and the arterial pressure \[[@CR67]\]. Vitamin E reduces the production of MDA by inhibiting lipid peroxidation, an important mechanism that causes
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the [*maximum*]{} value of $g$ over all simple paths with $m_1$ edges and $m_2$ interior vertices. In particular, $g(G)\le 2m_1$ for any graph $G$ with $m_1$ edges and $m_2$ interior vertices. Let $G$ be a graph on $n$ vertices with $m_1$ edges and $m_2$ interior vertices, for some $n>0$. Then $g(G)\le 2m_1+3m_2$. Figure 2.3 Let $k=2m_1+2m_2$. To prove the theorem, we need to find $g\in L(G)$ with value equal to $k$ or greater. Consider $g_1$ the linear function defined by $$g_1(v)=\left\{\begin{array}{l} 1 \mbox{ if } v=v_1\\ 2 \mbox{ if } v=v_2\\ 0 \mbox{ otherwise.} \end{array}\right.$$ Each path with $m_1+m_2$ vertices has a one-to-one correspondence with a subset of the edges of $G$. The function $g_1$ maps an edge onto the number of edges in its set. Thus, $g_1\in L(G)$, and $g_1\ge k$ (due to the bound on the number of vertices in a simple path). This establishes $g(G)\le 2m_1+3m_2$. We have a more general statement for $m_1+m_2$ interior vertices for any value of $m_1$ and $m_2$. The same technique applies. However, it is well known (see [@graph]) that the numbers $g(G)$ for all graphs $G$ are bounded above by a constant $k$ independent of $G$. For any graph $G$ with $n$ vertices, there is a path $P$ in $G$ such that the function $g$ with $g(v)=1$ if $v\in V(P)$ and $g(v)=0$ otherwise is in $L(G)$ and has $g$
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Minimum: OS: Windows 7 Processor: Intel Core i3-2120 (3.1 GHz or AMD equivalent) Memory: 8GB RAM Hard disk: 25 GB available space Video: Intel HD graphics Additional Notes: DirectX 11 compatible video card is needed.
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